YIF1/YNL263C Summary Help

Standard Name YIF1
Systematic Name YNL263C
Feature Type ORF, Verified
Description Integral membrane protein; required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF3 (1, 2, 3, 4)
Name Description YIP1-Interacting Factor
Chromosomal Location
ChrXIV:147840 to 146896 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YIF1 GO evidence and references
  View Computational GO annotations for YIF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Large-scale survey
null
reduction of function
repressible
Resources
84 total interaction(s) for 54 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 5
  • Biochemical Activity: 4
  • Co-fractionation: 1
  • Co-purification: 2
  • Reconstituted Complex: 15
  • Two-hybrid: 34

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 13
  • Phenotypic Suppression: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 314
Molecular Weight (Da) 35,498
Isoelectric Point (pI) 9.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:147840 to 146896 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..945 147840..146896 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005207
References cited on this page View Complete Literature Guide for YIF1
1) Barrowman J, et al.  (2003) The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J Biol Chem 278(22):19878-84
2) Matern H, et al.  (2000) A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. EMBO J 19(17):4485-92
3) Heidtman M, et al.  (2005) Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Mol Biol Cell 16(4):1673-83
4) Tanimoto K, et al.  (2011) Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip domain family proteins. Cell Struct Funct 36(2):171-85