YIA6/YIL006W Summary Help

Standard Name YIA6 1
Systematic Name YIL006W
Alias NDT1 2
Feature Type ORF, Verified
Description Mitochondrial NAD+ transporter; involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs; YIA6 has a paralog, YEA6, that arose from the whole genome duplication (2, 3, 4)
Chromosomal Location
ChrIX:344062 to 345183 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YIA6 GO evidence and references
  View Computational GO annotations for YIA6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
14 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • PCA: 1
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 4
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 373
Molecular Weight (Da) 41,954
Isoelectric Point (pI) 8.9
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:344062 to 345183 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1122 344062..345183 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001268
References cited on this page View Complete Literature Guide for YIA6
1) El Moualij B, et al.  (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81
2) Todisco S, et al.  (2006) Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae. J Biol Chem 281(3):1524-31
3) Hildyard JC and Halestrap AP  (2003) Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae. Biochem J 374(Pt 3):607-11
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61