SPC97/YHR172W Summary Help

Standard Name SPC97
Systematic Name YHR172W
Feature Type ORF, Verified
Description Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque (1, 2)
Name Description Spindle Pole Component
Chromosomal Location
ChrVIII:448335 to 450806 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SPC97 GO evidence and references
  View Computational GO annotations for SPC97
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
conditional
overexpression
unspecified
Large-scale survey
conditional
null
overexpression
repressible
Resources
90 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 19
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 29
  • Co-localization: 1
  • Co-purification: 4
  • FRET: 7
  • Reconstituted Complex: 5
  • Two-hybrid: 11

Genetic Interactions
  • Dosage Lethality: 2
  • Dosage Rescue: 4
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 823
Molecular Weight (Da) 96,824
Isoelectric Point (pI) 6.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:448335 to 450806 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2472 448335..450806 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001215
References cited on this page View Complete Literature Guide for SPC97
1) Nguyen T, et al.  (1998) A genetic analysis of interactions with Spc110p reveals distinct functions of Spc97p and Spc98p, components of the yeast gamma-tubulin complex. Mol Biol Cell 9(8):2201-16
2) Knop M, et al.  (1997) The spindle pole body component Spc97p interacts with the gamma-tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplication. EMBO J 16(7):1550-64