| Standard Name | SAE3 |
|---|---|
| Systematic Name | YHR079C-A |
| Alias | YHR079C-B |
| Feature Type | ORF, Verified |
| Description | Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p (1, 2, 3, 4) Also known as: YHR079BC |
| Name Description | Sporulation in the Absence of spo Eleven 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All SAE3 GO evidence and references
| View Computational GO annotations for SAE3 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All SAE3 Phenotype evidence and references
| Classical genetics | |
|---|---|
| unspecified | |
| Large-scale survey | |
| null |
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| Resources |
interactions All SAE3 Interaction evidence and references
| 19 total interaction(s) for 13 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All SAE3 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 2005-11-03 | ||||||||||||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000001957 |
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References cited on this page View Complete Literature Guide for SAE3
| 1) | McKee AH and Kleckner N (1997) A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146(3):797-816 |
| 2) | McKee AH and Kleckner N (1997) Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics 146(3):817-34 |
| 3) | Hayase A, et al. (2004) A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1. Cell 119(7):927-40 |
| 4) | Tsubouchi H and Roeder GS (2004) The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination. Genetics 168(3):1219-30 |




