BRL1/YHR036W Summary Help

Standard Name BRL1 1
Systematic Name YHR036W
Feature Type ORF, Verified
Description Essential nuclear envelope integral membrane protein; identified as a suppressor of a conditional mutation in the major karyopherin, CRM1; homologous to and interacts with Brr6p, a nuclear envelope protein involved in nuclear export (1)
Name Description BRr6 Like protein 1
Chromosomal Location
ChrVIII:180345 to 181760 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All BRL1 GO evidence and references
  View Computational GO annotations for BRL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
unspecified
Resources
18 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 3
  • Negative Genetic: 3
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 471
Molecular Weight (Da) 53,385
Isoelectric Point (pI) 4.6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:180345 to 181760 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1416 180345..181760 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001078
References cited on this page View Complete Literature Guide for BRL1
1) Saitoh Yh, et al.  (2005) Brl1p -- a novel nuclear envelope protein required for nuclear transport. Traffic 6(6):502-17