NEL1/YHR035W Summary Help

Standard Name NEL1 1
Systematic Name YHR035W
Feature Type ORF, Verified
Description Activator of Sar1p GTPase activity; paralog of Sec23 but does not associate with the COPII components; not an essential gene (1, 2)
Name Description Non-ERES Localized Sec23 homolog 1 1
Chromosomal Location
ChrVIII:178219 to 180111 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NEL1 GO evidence and references
  View Computational GO annotations for NEL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Large-scale survey
null
unspecified
Resources
15 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 630
Molecular Weight (Da) 72,306
Isoelectric Point (pI) 8.59
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:178219 to 180111 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1893 178219..180111 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001077
References cited on this page View Complete Literature Guide for NEL1
1) Kodera C, et al.  (2014) Sec23 Homolog Nel1 Is a Novel GTPase-activating Protein for Sar1 but Does Not Function as a Subunit of the Coat Protein Complex II (COPII) Coat. J Biol Chem 289(31):21423-32
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91