| Systematic Name | YGR250C |
|---|---|
| Feature Type | ORF, Verified |
| Description | Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress (1, 2, 3, 4) |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All YGR250C GO evidence and references
| View Computational GO annotations for YGR250C | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated |
|
| Cellular Component | |
| Manually curated | |
| High-throughput |
Mutant phenotypes All YGR250C Phenotype evidence and references
| Large-scale survey | |
|---|---|
| null |
|
| overexpression | |
| Resources |
interactions All YGR250C Interaction evidence and references
| 64 total interaction(s) for 55 unique genes/features. | |
| Physical Interactions |
|
| Genetic Interactions |
|
| Resources |
|
Expression Summary
|
| |
| Resources |
Protein Information All YGR250C Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
|
| |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
| ||||||||||||
| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
|---|
| Primary SGDID | S000003482 |
|---|
References cited on this page View Complete Literature Guide for
| 1) | Feroli F, et al. (1997) Analysis of a 17.9 kb region from Saccharomyces cerevisiae chromosome VII reveals the presence of eight open reading frames, including BRF1 (TFIIIB70) and GCN5 genes. Yeast 13(4):373-7 |
| 2) | Buchan JR, et al. (2008) P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol 183(3):441-55 |
| 3) | Wout PK, et al. (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71 |
| 4) | Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 |




