MUP1/YGR055W Summary

MUP1 BASIC INFORMATION

Standard Name	MUP1
Systematic Name	YGR055W
Feature Type	ORF, Verified
Description	High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake (1, 2)
Name Description	Methionine UPtake

GO Annotations	All MUP1 GO evidence and references
	View Computational GO annotations for MUP1
Molecular Function
Manually curated	L-methionine secondary active transmembrane transporter activity (IDA)
Biological Process
Manually curated	sulfur amino acid transport (IMP)
Cellular Component
Manually curated	integral to plasma membrane (ISS)

Mutant Phenotype	All MUP1 Phenotype details and references
Classical genetics
null	toxin resistance: decreased
Large-scale survey
null	acid pH resistance: decreased resistance to rapamycin: decreased resistance to wortmannin: decreased resistance to hydroxyurea: decreased resistance to selenomethionine: increased toxin resistance: decreased viable

Interactions	MUP1 All interactions details and references
	63 total interaction(s) for 63 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 2 Affinity Capture-Western: 1 PCA: 52 Protein-RNA: 1 Two-hybrid: 3
Genetic Interactions	Dosage Rescue: 1 Phenotypic Suppression: 2

Sequence Information

ChrVII:599421 to 601145 | |

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1725	599421..601145	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000003287

MUP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MUP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MUP1]

1)	Isnard AD, et al. (1996) The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases. J Mol Biol 262(4):473-84
2)	Kosugi A, et al. (2001) MUP1, high affinity methionine permease, is involved in cysteine uptake by Saccharomyces cerevisiae. Biosci Biotechnol Biochem 65(3):728-31

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