| Standard Name | SUA5 1 |
|---|---|
| Systematic Name | YGL169W |
| Feature Type | ORF, Verified |
| Description | Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family (1, 2, 3, 4) |
| Name Description | Suppressor of Upstream AUG 1 |
| Chromosomal Location | |
|---|---|
| Genetic position: -104.06 cM |
Gene Ontology Annotations All SUA5 GO evidence and references
| View Computational GO annotations for SUA5 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| High-throughput |
Mutant phenotypes All SUA5 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null |
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| reduction of function | |
| Large-scale survey | |
| null | |
| reduction of function | |
| Resources |
interactions All SUA5 Interaction evidence and references
| 15 total interaction(s) for 14 unique genes/features. | |
| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All SUA5 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Genetic position: -104.06 cM | |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000003137 |
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References cited on this page View Complete Literature Guide for SUA5
| 1) | Hampsey M, et al. (1991) Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae. Biochimie 73(12):1445-55 |
| 2) | Na JG, et al. (1992) Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. Genetics 131(4):791-801 |
| 3) | El Yacoubi B, et al. (2009) The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. Nucleic Acids Res 37(9):2894-909 |
| 4) | Meng FL, et al. (2009) Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J 28(10):1466-78 |




