CUE3/YGL110C Summary Help

Standard Name CUE3 1
Systematic Name YGL110C
Feature Type ORF, Verified
Description Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination (1)
Name Description Coupling of Ubiquitin conjugation to ER degradation 2
Chromosomal Location
ChrVII:303411 to 301537 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CUE3 GO evidence and references
  View Computational GO annotations for CUE3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
38 total interaction(s) for 34 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Biochemical Activity: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 21
  • Positive Genetic: 1
  • Synthetic Growth Defect: 4
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 624
Molecular Weight (Da) 72,042
Isoelectric Point (pI) 6.97
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:303411 to 301537 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1875 303411..301537 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003078
References cited on this page View Complete Literature Guide for CUE3
1) Shih SC, et al.  (2003) A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J 22(6):1273-81
2) Biederer T, et al.  (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278(5344):1806-9