LCL3/YGL085W Summary Help

Standard Name LCL3 1
Systematic Name YGL085W
Feature Type ORF, Uncharacterized
Description Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS (1, 2, 3, 4)
Name Description Long Chronological Lifespan 3 1
Chromosomal Location
ChrVII:349616 to 350440 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All LCL3 GO evidence and references
  View Computational GO annotations for LCL3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Large-scale survey
null
Resources
8 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 4
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 274
Molecular Weight (Da) 32,112
Isoelectric Point (pI) 10.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:349616 to 350440 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..825 349616..350440 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003053
References cited on this page View Complete Literature Guide for LCL3
1) Matecic M, et al.  (2010) A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet 6(4):e1000921
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Ponting CP  (1997) P100, a transcriptional coactivator, is a human homologue of staphylococcal nuclease. Protein Sci 6(2):459-63
4) Lee MW, et al.  (2007) Global protein expression profiling of budding yeast in response to DNA damage. Yeast 24(3):145-54