SDS23/YGL056C Summary Help

Standard Name SDS23 1
Systematic Name YGL056C
Feature Type ORF, Verified
Description Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; SDS23 has a paralog, SDS24, that arose from the whole genome duplication (2, 3, 4)
Name Description homolog of S. pombe SDS23 2
Chromosomal Location
ChrVII:397618 to 396035 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SDS23 GO evidence and references
  View Computational GO annotations for SDS23
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 12 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
38 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 3
  • PCA: 17
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Negative Genetic: 3
  • Phenotypic Enhancement: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 527
Molecular Weight (Da) 58,098
Isoelectric Point (pI) 9.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:397618 to 396035 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1584 397618..396035 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003024
References cited on this page View Complete Literature Guide for SDS23
1) Tham, E., et al.  (1998) . Unpublished
2) Jones AL, et al.  (2000) SAC3 may link nuclear protein export to cell cycle progression. Proc Natl Acad Sci U S A 97(7):3224-9
3) Goldar M, et al.  (2005) Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants. Biosci Biotechnol Biochem 69(7):1422-6
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61