Standard Name	IRC5 1
Systematic Name	YFR038W
Feature Type	ORF, Verified
Description	Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci (1, 2)
Name Description	Increased Recombination Centers 1

Chromosomal Location	ChrVI:229380 to 231941 | ORF Map | GBrowse

	View Computational GO annotations for IRC5
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mitotic recombination (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Classical genetics
null	viable
Large-scale survey
null	competitive fitness: decreased mitotic recombination: increased Rad52-YFP distribution: increased resistance to sodium selenide: decreased resistance to cycloheximide: decreased resistance to streptomycin: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	52 total interaction(s) for 39 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Biochemical Activity: 5 Reconstituted Complex: 2 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 30 Phenotypic Enhancement: 1 Positive Genetic: 6 Synthetic Growth Defect: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:229380 to 231941 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2004-02-05
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2562 229380..231941 2011-02-03 2004-02-05
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001934