IRC5/YFR038W Summary Help

Standard Name IRC5 1
Systematic Name YFR038W
Feature Type ORF, Verified
Description Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci (1, 2)
Name Description Increased Recombination Centers 1
Chromosomal Location
ChrVI:229380 to 231941 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All IRC5 GO evidence and references
  View Computational GO annotations for IRC5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
55 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Biochemical Activity: 5
  • PCA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 30
  • Phenotypic Enhancement: 1
  • Positive Genetic: 6
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 853
Molecular Weight (Da) 96,965
Isoelectric Point (pI) 6.22
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVI:229380 to 231941 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2004-02-05
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2562 229380..231941 2011-02-03 2004-02-05
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001934
References cited on this page View Complete Literature Guide for IRC5
1) Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
2) Shiratori A, et al.  (1999) Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis. Yeast 15(3):219-53