Systematic Name	YFL052W
Feature Type	ORF, Uncharacterized
Description	Putative zinc cluster protein that contains a DNA binding domain; computational analysis suggests a role as a transcription factor; null mutant is sensitive to Calcofluor White, low osmolarity, and heat, suggesting a role for YFL052Wp in cell wall integrity (1, 2)

Chromosomal Location	ChrVI:28232 to 29629 | ORF Map | GBrowse

	View Computational GO annotations for YFL052W
Molecular Function
Manually curated	DNA binding (ISS)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cellular_component unknown (ND)

Retired Name	ROP1

Regulatory modules	predicted: stressResponse (649)
Resources	YeTFaSCo

Classical genetics
null	heat sensitivity: increased resistance to Calcofluor White: decreased respiratory metabolism: decreased viable
Large-scale survey
null	competitive fitness: increased haploinsufficient resistance to ketoconazole: normal resistance to benzo[a]pyrene: decreased resistance to 4-nitroquinoline N-oxide: normal resistance to oligomycin: normal resistance to rhodamine 6-G: normal resistance to cycloheximide: normal resistance to chloramphenicol: normal starvation resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	29 total interaction(s) for 28 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2
Genetic Interactions	Negative Genetic: 20 Positive Genetic: 5 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:28232 to 29629 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1398 28232..29629 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC9-8 S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain M22 S.c. Strain PW5 S.c. Strain T7 S.c. Strain UC5 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001842