YET3/YDL072C Summary Help

Standard Name YET3 1
Systematic Name YDL072C
Feature Type ORF, Verified
Description Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein; protein abundance increases in response to DNA replication stress (1, 2)
Name Description Yeast Endoplasmic reticulum Transmembrane protein 1
Chromosomal Location
ChrIV:330447 to 329836 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YET3 GO evidence and references
  View Computational GO annotations for YET3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
68 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 7
  • Co-purification: 1
  • Two-hybrid: 22

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 17
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 203
Molecular Weight (Da) 22,902
Isoelectric Point (pI) 7.19
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:330447 to 329836 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..612 330447..329836 2004-02-11 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002230
References cited on this page View Complete Literature Guide for YET3
1) Toikkanen JH, et al.  (2006) YET1, YET2 and YET3 of Saccharomyces cerevisiae Encode BAP31 Homologs with Partially Overlapping Functions. J. Biol. Sci. (Faisalabad) 6(3):446-456
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76