AIM11/YER093C-A Summary Help

Standard Name AIM11 1
Systematic Name YER093C-A
Alias GEP8 2
Feature Type ORF, Verified
Description Protein of unknown function; null mutant is viable but shows increased loss of mitochondrial genome and synthetic interaction with prohibitin (phb1); contains an intron; YER093C-A has a paralog, YBL059W, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description Altered Inheritance rate of Mitochondria 1
Chromosomal Location
ChrV:348400 to 347912 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All AIM11 GO evidence and references
  View Computational GO annotations for AIM11
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Large-scale survey
null
Resources
50 total interaction(s) for 47 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Co-purification: 1

Genetic Interactions
  • Negative Genetic: 36
  • Positive Genetic: 6
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 137
Molecular Weight (Da) 15,753
Isoelectric Point (pI) 10.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:348400 to 347912 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..124 348400..348277 2011-02-03 1996-07-31
Intron 125..199 348276..348202 2011-02-03 1996-07-31
CDS 200..489 348201..347912 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002960
References cited on this page View Complete Literature Guide for AIM11
1) Hess DC, et al.  (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
2) Osman C, et al.  (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96
3) Davis CA, et al.  (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6
4) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
5) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61