Standard Name	CEM1 1
Systematic Name	YER061C
Feature Type	ORF, Verified
Description	Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration (1, 2)
Name Description	Condensing Enzyme with Mitochondrial function 1

Chromosomal Location	ChrV:279626 to 278298 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CEM1
Molecular Function
Manually curated	3-oxoacyl-[acyl-carrier-protein] synthase activity (ISA)
Biological Process
Manually curated	fatty acid biosynthetic process (ISA)
Cellular Component
High-throughput	mitochondrion (IDA)

Pathways	fatty acid biosynthesis, initial steps fatty acid elongation myristate biosynthesis palmitate biosynthesis stearate biosynthesis superpathway of fatty acid biosynthesis, saturated superpathway of fatty acid biosynthesis, saturated and unsaturated

Classical genetics
null	mature RPM1 RNA accumulation: decreased tellurium atom accumulation: increased resistance to tellurite: decreased
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased heat sensitivity: increased resistance to trichothecene: increased resistance to 2,4-dichlorophenol: decreased resistance to methyl methanesulfonate: decreased resistance to elesclomol-Cu: decreased resistance to L-canavanine: increased respiratory growth: absent respiratory growth: decreased rate starvation resistance: decreased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	214 total interaction(s) for 166 unique genes/features.
Physical Interactions	Biochemical Activity: 1 PCA: 1
Genetic Interactions	Dosage Growth Defect: 2 Negative Genetic: 185 Positive Genetic: 18 Synthetic Growth Defect: 5 Synthetic Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:279626 to 278298 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1329 279626..278298 2011-02-03 2011-02-03
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000863