YER010C Summary Help

Systematic Name YER010C
Feature Type ORF, Verified
Description Bifunctional HMG aldolase/oxaloacetate decarboxylase; requires divalent metal ions for activity; competitively inhibited by oxalate; forms a ring-shaped homotrimer; similar to members of the prokaryotic RraA family of class II (divalent metal ion dependent) pyruvate aldolases from the meta cleavage pathways of protocatechuate and gallate (1, 2)
Chromosomal Location
ChrV:173338 to 172634 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YER010C GO evidence and references
  View Computational GO annotations for YER010C
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Large-scale survey
null
Resources
7 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 2
  • Two-hybrid: 1

Genetic Interactions
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 234
Molecular Weight (Da) 25,563
Isoelectric Point (pI) 7.43
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:173338 to 172634 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..705 173338..172634 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000812
References cited on this page View Complete Literature Guide for YER010C
1) Leulliot N, et al.  (2005) Crystal structure of yeast YER010Cp, a knotable member of the RraA protein family. Protein Sci 14(10):2751-8
2) Mazurkewich S, et al.  (2014) Biochemical and structural analysis of RraA proteins to decipher their relationships with 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolases. Biochemistry 53(3):542-53