BUD16/YEL029C Summary Help

Standard Name BUD16 1
Systematic Name YEL029C
Feature Type ORF, Verified
Description Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK) (1, 2, 3, 4)
Name Description BUD site selection 1
Chromosomal Location
ChrV:97796 to 96858 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All BUD16 GO evidence and references
  View Computational GO annotations for BUD16
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Regulators 55 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
20 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Reconstituted Complex: 8
  • Two-hybrid: 1

Genetic Interactions
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 312
Molecular Weight (Da) 35,559
Isoelectric Point (pI) 6.51
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:97796 to 96858 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..939 97796..96858 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000755
References cited on this page View Complete Literature Guide for BUD16
1) Ni L and Snyder M  (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70
2) Hanna MC, et al.  (1997) Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor. J Biol Chem 272(16):10756-60
3) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63
4) Kanellis P, et al.  (2007) A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS Genet 3(8):e134