YEH1/YLL012W Summary Help

Standard Name YEH1 1
Systematic Name YLL012W
Feature Type ORF, Verified
Description Steryl ester hydrolase; one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes; YEH1 has a paralog, YEH2, that arose from the whole genome duplication (1, 2)
Name Description Yeast steryl Ester Hydrolase 1
Chromosomal Location
ChrXII:125534 to 127255 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YEH1 GO evidence and references
  View Computational GO annotations for YEH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 11 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
36 total interaction(s) for 34 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • PCA: 5

Genetic Interactions
  • Negative Genetic: 7
  • Phenotypic Enhancement: 2
  • Positive Genetic: 7
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 573
Molecular Weight (Da) 66,507
Isoelectric Point (pI) 6.63
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:125534 to 127255 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1722 125534..127255 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003935
References cited on this page View Complete Literature Guide for YEH1
1) Koffel R, et al.  (2005) The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis. Mol Cell Biol 25(5):1655-68
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61