Standard Name	PAD1 1
Systematic Name	YDR538W
Alias	POF1
Feature Type	ORF, Verified
Description	Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; also has mRNA binding activity; homolog of E. coli UbiX (1, 2, 3, 4)
Name Description	Phenylacrylic Acid Decarboxylase 1

Chromosomal Location	ChrIV:1510902 to 1511630 | ORF Map | GBrowse

	View Computational GO annotations for PAD1
Molecular Function
Manually curated	carboxy-lyase activity (IMP) mRNA binding (IDA)
Biological Process
Manually curated	aromatic compound catabolic process (IMP) cinnamic acid catabolic process (IMP)
Cellular Component
Manually curated	mitochondrion (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	resistance to cinnamic acid: decreased viable
overexpression	ethanol accumulation: increased rate resistance to cinnamic acid: increased resistance to ferulic acid: increased utilization of carbon source: increased rate utilization of carbon source: increased
unspecified	resistance to cinnamic acid: decreased
Large-scale survey
null	competitive fitness: normal haploinsufficient resistance to cycloheximide: decreased resistance to streptomycin: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	12 total interaction(s) for 12 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-Western: 1
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Negative Genetic: 7 Phenotypic Enhancement: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1510902 to 1511630 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..729 1510902..1511630 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002946