RAV2/YDR202C Summary Help

Standard Name RAV2 1
Systematic Name YDR202C
Feature Type ORF, Verified
Description Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme (1, 2)
Name Description Regulator of (H+)-ATPase in Vacuolar membrane 1
Chromosomal Location
ChrIV:857953 to 856898 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RAV2 GO evidence and references
  View Computational GO annotations for RAV2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Large-scale survey
null
Resources
113 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 6
  • PCA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 78
  • Positive Genetic: 9
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 351
Molecular Weight (Da) 40,017
Isoelectric Point (pI) 6.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:857953 to 856898 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1056 857953..856898 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002610
References cited on this page View Complete Literature Guide for RAV2
1) Seol JH, et al.  (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91
2) Smardon AM, et al.  (2002) The RAVE complex is essential for stable assembly of the yeast V-ATPase. J Biol Chem 277(16):13831-9