CAB5/YDR196C Summary Help

CAB5 BASIC INFORMATION

Standard Name CAB5 1
Systematic Name YDR196C
Feature Type ORF, Verified
Description Probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies (1, 2, 3, 4, 5)
GO Annotations All CAB5 GO evidence and references
    View Computational GO annotations for CAB5
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
High-throughput
Pathways
Mutant Phenotype All CAB5 Phenotype details and references
Classical genetics
conditional
null
Large-scale survey
conditional
null
Interactions CAB5 All interactions details and references
22 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
Genetic Interactions
  • Phenotypic Enhancement: 16
  • Phenotypic Suppression: 2
  • Synthetic Lethality: 1
Sequence Information
ChrIV:850997 to 850272 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..726 850997..850272 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002604

CAB5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CAB5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CAB5]

1) Olzhausen J, et al.  (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Tatusov RL, et al.  (2000) The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res 28(1):33-6
4) Daugherty M, et al.  (2002) Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 277(24):21431-9
5) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54