RVB1/YDR190C Summary Help

RVB1 BASIC INFORMATION

Standard Name RVB1
Systematic Name YDR190C
Alias TIP49A , TIH1 , TIP48 1
Feature Type ORF, Verified
Description Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as pontin; member of the RUVB-like protein family (1, 2, 3, 4)
Name Description RuVB-like 3
GO Annotations All RVB1 GO evidence and references
    View Computational GO annotations for RVB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All RVB1 Phenotype details and references
Large-scale survey
null
overexpression
Interactions RVB1 All interactions details and references
168 total interaction(s) for 86 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 127
  • Affinity Capture-Western: 10
  • Biochemical Activity: 2
  • Co-crystal Structure: 1
  • Co-purification: 2
  • PCA: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 5
Genetic Interactions
  • Phenotypic Enhancement: 15
  • Phenotypic Suppression: 2
Sequence Information
ChrIV:841993 to 840602 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1392 841993..840602 2008-06-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002598

RVB1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for RVB1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RVB1]

1) Jonsson ZO, et al.  (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77
2) Qiu XB, et al.  (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93
3) Jonsson ZO, et al.  (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88
4) Torreira E, et al.  (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20