KIN1/YDR122W Summary Help

Standard Name KIN1 1
Systematic Name YDR122W
Feature Type ORF, Verified
Description Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN1 has a paralog, KIN2, that arose from the whole genome duplication (1, 2, 3)
Name Description KINase 1
Chromosomal Location
ChrIV:694700 to 697894 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All KIN1 GO evidence and references
  View Computational GO annotations for KIN1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
124 total interaction(s) for 91 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Biochemical Activity: 3
  • Co-purification: 1
  • PCA: 8
  • Reconstituted Complex: 5
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 11
  • Dosage Rescue: 10
  • Negative Genetic: 48
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,064
Molecular Weight (Da) 120,070
Isoelectric Point (pI) 9.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:694700 to 697894 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3195 694700..697894 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002529
References cited on this page View Complete Literature Guide for KIN1
1) Levin DE, et al.  (1987) Two yeast genes that encode unusual protein kinases. Proc Natl Acad Sci U S A 84(17):6035-9
2) Elbert M, et al.  (2005) The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Mol Biol Cell 16(2):532-49
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61