Standard Name	ARX1 1
Systematic Name	YDR101C
Feature Type	ORF, Verified
Description	Nuclear export factor for the ribosomal pre-60S subunit; shuttling factor which directly binds FG rich nucleoporins and facilities translocation through the nuclear pore complex; interacts directly with Alb1p; responsible for Tif6p recycling defects in the absence of Rei1; associated with the ribosomal export complex (2, 3, 4, 5)
Name Description	Associated with Ribosomal eXport complex 1

Chromosomal Location	ChrIV:657467 to 655686 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for ARX1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ribosomal large subunit export from nucleus (IGI, IMP)
Cellular Component
Manually curated	cytoplasm (IDA) colocalizes_with cytosolic large ribosomal subunit (IDA) nucleoplasm (IDA)

Classical genetics
null	Rpl25-enhanced GFP distribution: decreased viable
Large-scale survey
null	budding index: increased cell size: decreased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate haploproficient resistance to doxorubicin: decreased resistance to L-1,4-dithiothreitol: decreased toxin resistance: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	414 total interaction(s) for 143 unique genes/features.
Physical Interactions	Affinity Capture-MS: 167 Affinity Capture-Western: 101 Co-purification: 5 PCA: 1 Reconstituted Complex: 15 Two-hybrid: 6
Genetic Interactions	Dosage Growth Defect: 1 Dosage Lethality: 1 Dosage Rescue: 4 Negative Genetic: 59 Phenotypic Enhancement: 2 Phenotypic Suppression: 1 Positive Genetic: 8 Synthetic Growth Defect: 28 Synthetic Lethality: 12 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:657467 to 655686 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1782 657467..655686 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002508