Standard Name	SHU2 1
Systematic Name	YDR078C
Feature Type	ORF, Verified
Description	Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function (1, 2, 3, 4, 5)
Name Description	Suppressor of HydroxyUrea sensitivity 1

Chromosomal Location	ChrIV:602869 to 602198 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SHU2
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	error-free translesion synthesis (IC) maintenance of rDNA (IGI) recombinational repair (IGI)
Cellular Component
Manually curated	Shu complex (IPI)

Classical genetics
null	resistance to methyl methanesulfonate: decreased
Large-scale survey
null	acid pH resistance: decreased haploproficient hyperosmotic stress resistance: decreased Fus-Mid-GFP distribution: abnormal resistance to 2,4-dichlorophenol: decreased resistance to pentachlorophenol: decreased resistance to methyl methanesulfonate: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	31 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 3 Co-purification: 1 Two-hybrid: 7
Genetic Interactions	Negative Genetic: 4 Phenotypic Suppression: 1 Positive Genetic: 6 Synthetic Growth Defect: 3 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:602869 to 602198 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..672 602869..602198 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002485