HBT1/YDL223C Summary Help

Standard Name HBT1 1
Systematic Name YDL223C
Feature Type ORF, Verified
Description Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication (1, 2)
Name Description HuB1 Target 1
Chromosomal Location
ChrIV:60405 to 57265 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All HBT1 GO evidence and references
  View Computational GO annotations for HBT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 146 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
56 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 9

Genetic Interactions
  • Negative Genetic: 26
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,046
Molecular Weight (Da) 113,616
Isoelectric Point (pI) 6.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:60405 to 57265 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3141 60405..57265 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002382
References cited on this page View Complete Literature Guide for HBT1
1) Dittmar GA, et al.  (2002) Role of a ubiquitin-like modification in polarized morphogenesis. Science 295(5564):2442-6
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61