COP1/YDL145C Summary Help

COP1 BASIC INFORMATION

Standard Name COP1
Systematic Name YDL145C
Alias SEC33 , RET1 , SOO1 1
Feature Type ORF, Verified
Description Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway (2)
Name Description COat Protein
GO Annotations All COP1 GO evidence and references
    View Computational GO annotations for COP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All COP1 Phenotype details and references
Classical genetics
conditional
repressible
Large-scale survey
null
overexpression
Interactions COP1 All interactions details and references
94 total interaction(s) for 52 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 68
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 9
  • Protein-peptide: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 7
Sequence Information
ChrIV:198177 to 194572 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3606 198177..194572 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002304

COP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for COP1

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
RET1Nomenclature conflictRET1 has been used in the literature to refer to both COP1/YDL145C (Letourneur, F. et al. (1994) Cell 79:1199; PMID:8001155), which encodes a coatomer complex alpha subunit, and RET1/YOR207C (James, P. et al. (1991) JBC 266:5616; PMID:2005101), which encodes a subunit of RNA polymerase III.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for COP1]

1) Lee DW, et al.  (1999) Identification of a gene, SOO1, which complements osmo-sensitivity and defect in in vitro beta1,3-glucan synthase activity in Saccharomyces cerevisiae. Biochim Biophys Acta 1450(2):145-54
2) Gerich B, et al.  (1995) Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth. Proc Natl Acad Sci U S A 92(8):3229-33