NDE2/YDL085W Summary Help

NDE2 BASIC INFORMATION

Standard Name NDE2
Systematic Name YDL085W
Alias NDH2
Feature Type ORF, Verified
Description Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain (1, 2, 3)
Name Description NADH Dehydrogenase, External 2
GO Annotations All NDE2 GO evidence and references
    View Computational GO annotations for NDE2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All NDE2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions NDE2 All interactions details and references
  View additional details at BioGRID
33 total interaction(s) for 32 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • PCA: 3
Genetic Interactions
  • Negative Genetic: 18
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 3
Sequence Information
ChrIV:303211 to 304848 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1638 303211..304848 2004-02-11 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002243

NDE2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Phenotype Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for NDE2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NDE2]

1) Overkamp KM, et al.  (2000) In vivo analysis of the mechanisms for oxidation of cytosolic NADH by Saccharomyces cerevisiae mitochondria. J Bacteriol 182(10):2823-30
2) Luttik MA, et al.  (1998) The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH. J Biol Chem 273(38):24529-34
3) Pahlman IL, et al.  (2002) Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae. J Biol Chem 277(31):27991-5