Standard Name	VAC17 1, 2
Systematic Name	YCL063W
Alias	YCL062W
Feature Type	ORF, Verified
Description	Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p (1, 2, 3)
Name Description	VACuole related 1

Chromosomal Location	ChrIII:17290 to 18561 | ORF Map | GBrowse

	View Computational GO annotations for VAC17
Molecular Function
Manually curated	protein anchor (IPI)
Biological Process
Manually curated	vacuole inheritance (IEP, IGI, IMP, IPI)
Cellular Component
Manually curated	fungal-type vacuole membrane (IDA)

Classical genetics
null	metal resistance: decreased
Large-scale survey
null	competitive fitness: decreased haploinsufficient Pho8p (ALP) modification: decreased Cps1p (CPS) modification: decreased resistance to hydrogen chloride: increased resistance to arsenite(3-): decreased resistance to sodium selenide: decreased resistance to wortmannin: normal resistance to sirolimus: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	63 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-Western: 5 Biochemical Activity: 1 PCA: 1 Reconstituted Complex: 1 Two-hybrid: 11
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Negative Genetic: 33 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Positive Genetic: 2 Synthetic Growth Defect: 4 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIII:17290 to 18561 | ORF Map | GBrowse
	This feature contains embedded feature(s): YCL062W
Last Update	Coordinates: 2000-09-13 | Sequence: 2000-09-13
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1272 17290..18561 2000-09-13 2000-09-13
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000568