RRP7/YCL031C Summary Help

Standard Name RRP7 1
Systematic Name YCL031C
Feature Type ORF, Verified
Description Essential protein involved in rRNA processing and ribosome biogenesis; protein abundance increases in response to DNA replication stress (1, 2)
Name Description Ribosomal RNA Processing 1
Chromosomal Location
ChrIII:65568 to 64675 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RRP7 GO evidence and references
  View Computational GO annotations for RRP7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
reduction of function
Resources
92 total interaction(s) for 81 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 39
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Two-hybrid: 14

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 2
  • Negative Genetic: 12
  • Positive Genetic: 16

Resources
Expression Summary
histogram
Resources
Length (a.a.) 297
Molecular Weight (Da) 34,470
Isoelectric Point (pI) 9.55
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:65568 to 64675 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2000-09-13 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..894 65568..64675 2000-09-13 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000536
References cited on this page View Complete Literature Guide for RRP7
1) Baudin-Baillieu A, et al.  (1997) Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Mol Cell Biol 17(9):5023-32
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76