| Standard Name | HBN1 1 |
|---|---|
| Systematic Name | YCL026C-B |
| Alias | YCL027C-A |
| Feature Type | ORF, Verified |
| Description | Protein of unknown function; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein becomes insoluble upon intracellular iron depletion; protein abundance increases in response to DNA replication stress (1, 2, 3, 4) |
| Name Description | Homologous to Bacterial Nitroreductases 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All HBN1 GO evidence and references
| View Computational GO annotations for HBN1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated |
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| Cellular Component | |
| High-throughput |
Mutant phenotypes All HBN1 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null |
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| Large-scale survey | |
| null | |
| Resources |
interactions All HBN1 Interaction evidence and references
| 5 total interaction(s) for 4 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All HBN1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2000-09-14 | Sequence: 2000-09-14 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000007548 |
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References cited on this page View Complete Literature Guide for HBN1
| 1) | de Oliveira IM, et al. (2007) In silico identification of a new group of specific bacterial and fungal nitroreductases-like proteins. Biochem Biophys Res Commun 355(4):919-25 |
| 2) | Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 |
| 3) | Seo HY, et al. (2008) Proteomic Analysis of Recombinant Saccharomyces cerevisiae Upon Iron Deficiency Induced via Human H-Ferritin Production. J Microbiol Biotechnol 18(8):1368-76 |
| 4) | Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 |






