| Systematic Name | YBR284W |
|---|---|
| Feature Type | ORF, Uncharacterized |
| Description | Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; null mutant exhibits longer telomeres, altered Ty mobility, decreased resistance to rapamycin and wortmannin; induced in response to hydrostatic pressure; not an essential gene; YBR284W has a paralog, YJL070C, that arose from the whole genome duplication (1, 2, 3, 4, 5, 6, 7, 8) |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All YBR284W GO evidence and references
| View Computational GO annotations for YBR284W | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated |
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| Cellular Component | |
| Manually curated |
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Mutant phenotypes All YBR284W Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| unspecified | |
| Large-scale survey | |
| null |
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| overexpression | |
| Resources |
interactions All YBR284W Interaction evidence and references
| 22 total interaction(s) for 22 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All YBR284W Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1997-01-28 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000000488 |
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References cited on this page View Complete Literature Guide for YBR284W
| 1) | Holmstrom K, et al. (1994) The sequence of a 32,420 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae. Yeast 10 Suppl A:S47-62 |
| 2) | Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 |
| 3) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 4) | Willingham S, et al. (2003) Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science 302(5651):1769-72 |
| 5) | Gatbonton T, et al. (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35 |
| 6) | Maxwell PH and Curcio MJ (2007) Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retroviruses. Eukaryot Cell 6(7):1069-80 |
| 7) | Iwahashi H, et al. (2003) Piezophysiology of genome wide gene expression levels in the yeast Saccharomyces cerevisiae. Extremophiles 7(4):291-8 |
| 8) | Saint-Marc C, et al. (2009) Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 183(2):529-38, 1SI-7SI |





