Standard Name	RIB5 1
Systematic Name	YBR256C
Feature Type	ORF, Verified
Description	Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway (2)
Name Description	RIBoflavin biosynthesis 1

Chromosomal Location	ChrII:728102 to 727386 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 150 cM

	View Computational GO annotations for RIB5
Molecular Function
Manually curated	riboflavin synthase activity (IDA, ISS)
Biological Process
Manually curated	riboflavin biosynthetic process (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Pathways	riboflavin, FMN and FAD biosynthesis

Classical genetics
unspecified	auxotrophy 6,7-dimethyl-8-ribityllumazine accumulation: increased
Large-scale survey
conditional	heat sensitivity: increased redox state: abnormal
null	inviable
reduction of function	competitive fitness: decreased resistance to sirolimus: decreased resistance to hydroxyurea: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 4 PCA: 2
Genetic Interactions	Negative Genetic: 6 Phenotypic Enhancement: 3 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:728102 to 727386 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 150 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..717 728102..727386 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000460