Standard Name	AIM4 1
Systematic Name	YBR194W
Alias	SOY1 2 , 3
Feature Type	ORF, Verified
Description	Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress (1, 4, 5)
Name Description	Altered Inheritance rate of Mitochondria 1

Chromosomal Location	ChrII:610038 to 610409 | ORF Map | GBrowse

	View Computational GO annotations for AIM4
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cytoplasm (IDA)

Classical genetics
null	viable
Large-scale survey
null	UV resistance: decreased bud morphology: abnormal glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate freeze-thaw resistance: decreased heat sensitivity: increased mitochondrial genome maintenance: abnormal oxidative stress resistance: decreased resistance to acetic acid: increased resistance to hydrogen chloride: increased resistance to bleomycin: increased resistance to cycloheximide: increased resistance to caffeine: increased resistance to fluconazole: increased resistance to mycophenolic acid: increased resistance to tunicamycin: increased resistance to ethanol: decreased resistance to glucose: decreased resistance to methyl methanesulfonate: decreased resistance to 4-nitroquinoline N-oxide: decreased resistance to pentachlorophenol: decreased resistance to camptothecin: increased resistance to cycloheximide: decreased resistance to hygromycin B: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	307 total interaction(s) for 287 unique genes/features.
Physical Interactions	Affinity Capture-MS: 157 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Co-purification: 1 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 115 Positive Genetic: 10 Synthetic Growth Defect: 13 Synthetic Lethality: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:610038 to 610409 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..372 610038..610409 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000398