Standard Name	AIM3 1
Systematic Name	YBR108W
Feature Type	ORF, Verified
Description	Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss (1, 2, 3)
Name Description	Altered Inheritance rate of Mitochondria 1

Chromosomal Location	ChrII:454822 to 457665 | ORF Map | GBrowse

	View Computational GO annotations for AIM3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	actin cortical patch assembly (IGI)
Cellular Component
Manually curated	actin cortical patch (IDA) colocalizes_with membrane raft (IDA)

Large-scale survey
null	competitive fitness: decreased haploproficient mitochondrial genome maintenance: abnormal resistance to camptothecin: increased resistance to cycloheximide: decreased resistance to streptomycin: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to tunicamycin: decreased resistance to hydroxyurea: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	217 total interaction(s) for 149 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 18 Protein-peptide: 3 Reconstituted Complex: 1 Two-hybrid: 18
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 114 Positive Genetic: 50 Synthetic Growth Defect: 3 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:454822 to 457665 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2844 454822..457665 2011-02-03 2011-02-03
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000312