PBY1/YBR094W Summary Help

Standard Name PBY1 1
Systematic Name YBR094W
Feature Type ORF, Verified
Description Putative tubulin tyrosine ligase associated with P-bodies; forms cytoplasmic foci upon DNA replication stress (1, 2)
Name Description P-BodY associated protein 1
Chromosomal Location
ChrII:432036 to 434297 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PBY1 GO evidence and references
  View Computational GO annotations for PBY1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
105 total interaction(s) for 67 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • PCA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 49
  • Phenotypic Enhancement: 3
  • Positive Genetic: 3
  • Synthetic Growth Defect: 19
  • Synthetic Lethality: 15

Resources
Expression Summary
histogram
Resources
Length (a.a.) 753
Molecular Weight (Da) 86,353
Isoelectric Point (pI) 4.55
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:432036 to 434297 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2262 432036..434297 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000298
References cited on this page View Complete Literature Guide for PBY1
1) Sweet TJ, et al.  (2007) Microtubule disruption stimulates P-body formation. RNA 13(4):493-502
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76