BAP2/YBR068C Summary

BAP2 BASIC INFORMATION

Standard Name	BAP2
Systematic Name	YBR068C
Feature Type	ORF, Verified
Description	High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains (1)
Name Description	Branched-chain Amino acid Permease 1

GO Annotations	All BAP2 GO evidence and references
	View Computational GO annotations for BAP2
Molecular Function
Manually curated	amino acid transmembrane transporter activity (IDA)
Biological Process
Manually curated	amino acid transport (IDA) transmembrane transport (IDA)
Cellular Component
Manually curated	plasma membrane (ISS)

Mutant Phenotype	All BAP2 Phenotype details and references
Classical genetics
null	nutrient uptake: decreased
Large-scale survey
null	acid pH resistance: decreased competitive fitness: decreased resistance to mycophenolic acid: decreased resistance to 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid: decreased viable
overexpression	vegetative growth: decreased

Interactions	BAP2 All interactions details and references
	18 total interaction(s) for 17 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 PCA: 8 Two-hybrid: 5
Genetic Interactions	Dosage Rescue: 2 Phenotypic Suppression: 1 Synthetic Growth Defect: 1

Sequence Information

ChrII:375687 to 373858 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-16 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1830	375687..373858	2004-07-16	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000000272

BAP2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BAP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BAP2]

1)	Grauslund M, et al. (1995) BAP2, a gene encoding a permease for branched-chain amino acids in Saccharomyces cerevisiae. Biochim Biophys Acta 1269(3):275-80

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