CMC2/YBL059C-A Summary Help

Standard Name CMC2 1, 2
Systematic Name YBL059C-A
Feature Type ORF, Verified
Description Protein involved in respiratory chain complex assembly or maintenance; protein of the mitochondrial intermembrane space; contains twin Cx9C motifs that can form coiled coil-helix-coiled-coil helix fold (1, 3)
Name Description Cx9C Motif-Containing protein 1
Chromosomal Location
ChrII:110539 to 110125 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CMC2 GO evidence and references
  View Computational GO annotations for CMC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Resources
6 total interaction(s) for 4 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Co-fractionation: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 109
Molecular Weight (Da) 12,947
Isoelectric Point (pI) 8.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:110539 to 110125 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2000-12-01
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..34 110539..110506 2011-02-03 2000-12-01
Intron 35..119 110505..110421 2011-02-03 2000-12-01
CDS 120..415 110420..110125 2011-02-03 2000-12-01
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000007488
References cited on this page View Complete Literature Guide for CMC2
1) Longen S, et al.  (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68
2) Horn D, et al.  (2010) The conserved mitochondrial twin Cx9C protein Cmc2 Is a Cmc1 homologue essential for cytochrome c oxidase biogenesis. J Biol Chem 285(20):15088-99
3) Gabriel K, et al.  (2007) Novel Mitochondrial Intermembrane Space Proteins as Substrates of the MIA Import Pathway. J Mol Biol 365(3):612-620