YAR061W Summary Help

Systematic Name YAR061W
Feature Type pseudogene
Description Pseudogenic fragment with similarity to flocculins; YAR061W has a paralog, YHR212W-A, that arose from a segmental duplication (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrI:218140 to 218343 | ORF Map | GBrowse
Gene Ontology Annotations All YAR061W GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Large-scale survey
1 total interaction(s) for 1 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1

Expression Summary
Length (a.a.) 67
Molecular Weight (Da) 7,610
Isoelectric Point (pI) 9.29
Phosphorylation PhosphoGRID
sequence information
ChrI:218140 to 218343 | ORF Map | GBrowse
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Most Recent Updates
Coordinates Sequence
CDS 1..204 218140..218343 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000087

Flocculation, the calcium-dependent, non-sexual aggregation of yeast cells into 'flocs', is stimulated by nutrient limitation and is a process of great importance to the brewing characteristics of yeast strains (1). Characterization of flocculation characteristics has defined two classes of flocculation phenotypes. The FLO1-type is inhibited only by mannose sugars (3). The NewFLO-type, common in brewing strains, is inhibited by the sugars mannose, maltose, glucose, and sucrose, as well as by ammonium ions (3).

Sequence analysis suggests that the flocculation genes are a multi-gene family localized to telomeric sequences, similarly to the SUC, MEL, and MAL gene families, all of which also encode characteristics important for brewing strains (1). In addition to FLO1 and FLO5, there are thought to be two more flocculation genes and three pseudogenes. The FLO9 gene (YAL063C) is 94% similar to the FLO1 gene and may be the source of a 4.2-kb transcript whose presence is not affected by deletions of FLO1 or FLO5. The FLO10 gene (YKR102W) is 58% similar to FLO1, but has 81.9% similarity in the N-terminus (1). Three presumed pseudogenes, YAL065C, YAR061W and YAR062W, and YHR213W have also been identified as fragmentary pieces with sequence similarity to FLO1 (1).

Last updated: 2004-02-09 Contact SGD

References cited on this page View Complete Literature Guide for YAR061W
1) Teunissen AW and Steensma HY  (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11(11):1001-13
2) Katju V, et al.  (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75
3) Stratford M  (1989) Evidence for two mechanisms of flocculation in Saccharomyces cerevisiae. Yeast 5 Spec No():S441-5