Standard Name	KIN3 (see Nomenclature conflict Note)
Systematic Name	YAR018C
Alias	FUN52 1 , NPK1
Feature Type	ORF, Verified
Description	Nonessential serine/threonine protein kinase; possible role in DNA damage response (2, 3)
Name Description	protein KINase

Chromosomal Location	ChrI:171703 to 170396 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for KIN3
Molecular Function
Manually curated	protein kinase activity (ISS)
High-throughput	protein kinase activity (IDA)
Biological Process
Manually curated	chromosome segregation (IMP)
High-throughput	protein phosphorylation (IDA)
Cellular Component
Manually curated	cellular_component unknown (ND)

Classical genetics
overexpression	cell cycle progression in G2 phase: abnormal cellular morphology: abnormal
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to sirolimus: decreased resistance to hygromycin B: decreased resistance to methyl methanesulfonate: decreased resistance to wortmannin: normal resistance to PM02734: decreased resistance to L-1,4-dithiothreitol: decreased resistance to tunicamycin: decreased resistance to benzo[a]pyrene: decreased viable
overexpression	vegetative growth: decreased rate vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	296 total interaction(s) for 237 unique genes/features.
Physical Interactions	Affinity Capture-MS: 13 Affinity Capture-Western: 1 Biochemical Activity: 4 Reconstituted Complex: 1 Two-hybrid: 106
Genetic Interactions	Dosage Growth Defect: 6 Negative Genetic: 122 Phenotypic Enhancement: 2 Phenotypic Suppression: 23 Positive Genetic: 14 Synthetic Growth Defect: 3 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:171703 to 170396 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1308 171703..170396 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000071