YAP5/YIR018W Summary Help

Standard Name YAP5 1
Systematic Name YIR018W
Feature Type ORF, Verified
Description Basic leucine zipper (bZIP) iron-sensing transcription factor; involved in diauxic shift; YAP5 has a paralog, YAP7, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Yeast AP-1 1
Chromosomal Location
ChrIX:384609 to 385346 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YAP5 GO evidence and references
  View Computational GO annotations for YAP5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 465 genes
Regulators 11 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
27 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • FRET: 1
  • PCA: 1
  • Protein-peptide: 1
  • Two-hybrid: 6

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Positive Genetic: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 245
Molecular Weight (Da) 28,386
Isoelectric Point (pI) 8.81
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:384609 to 385346 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..738 384609..385346 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001457
References cited on this page View Complete Literature Guide for YAP5
1) Fernandes L, et al.  (1997) Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol 17(12):6982-93
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Li L, et al.  (2008) Yap5 is an iron-responsive transcriptional activator that regulates vacuolar iron storage in yeast. Mol Cell Biol 28(4):1326-37
4) Zampar GG, et al.  (2013) Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast. Mol Syst Biol 9():651