YAP1801/YHR161C Summary Help

Standard Name YAP1801 1
Systematic Name YHR161C
Feature Type ORF, Verified
Description Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1801 has a paralog, YAP1802, that arose from the whole genome duplication (1, 2)
Name Description Yeast Assembly Polypeptide 1
Chromosomal Location
ChrVIII:422286 to 420373 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YAP1801 GO evidence and references
  View Computational GO annotations for YAP1801
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 12 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
76 total interaction(s) for 66 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 2
  • Co-localization: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 11

Genetic Interactions
  • Dosage Growth Defect: 3
  • Dosage Lethality: 1
  • Negative Genetic: 32
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 637
Molecular Weight (Da) 71,660
Isoelectric Point (pI) 7.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:422286 to 420373 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1914 422286..420373 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001204
References cited on this page View Complete Literature Guide for YAP1801
1) Wendland B and Emr SD  (1998) Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis. J Cell Biol 141(1):71-84
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61