WHI2/YOR043W Summary Help

WHI2 BASIC INFORMATION

Standard Name WHI2 1
Systematic Name YOR043W
Feature Type ORF, Verified
Description Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression (2, 3, 4)
Name Description WHIskey 3, 5
GO Annotations All WHI2 GO evidence and references
    View Computational GO annotations for WHI2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All WHI2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions WHI2 All interactions details and references
  View additional details at BioGRID
262 total interaction(s) for 205 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Two-hybrid: 7
Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 193
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 1
  • Positive Genetic: 12
  • Synthetic Growth Defect: 15
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 8
  • Synthetic Rescue: 5
Sequence Information
ChrXV:410870 to 412330 | ORF Map | GBrowse
Gbrowse
Genetic position: 9 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1461 410870..412330 2006-01-05 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005569

WHI2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for WHI2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for WHI2]

1) Sudbery, P.E.  (1989) Personal Communication, Mortimer Map Edition 10
2) Radcliffe P, et al.  (1997) Deregulation of CLN1 and CLN2 in the Saccharomyces cerevisiae whi2 mutant. Yeast 13(8):707-15
3) Sudbery PE, et al.  (1980) Genes which control cell proliferation in the yeast Saccharomyces cerevisiae. Nature 288(5789):401-4
4) Kaida D, et al.  (2002) Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression. Genes Cells 7(6):543-52
5) Saul DJ and Sudbery PE  (1985) Molecular cloning of WHI2, a gene involved in the regulation of cell proliferation in Saccharomyces cerevisiae. J Gen Microbiol 131(7):1797-806