VTH2/YJL222W Summary

VTH2/YJL222W Summary

Standard Name	VTH2
Systematic Name	YJL222W
Feature Type	ORF, Verified
Description	Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting (1, 2)

Chromosomal Location	ChrX:11475 to 16124 \| ORF Map \| GBrowse

Gene Ontology Annotations All VTH2 GO evidence and references

	View Computational GO annotations for VTH2
Molecular Function
Manually curated	signal sequence binding (IGI, ISA)
Biological Process
Manually curated	Golgi to vacuole transport (IGI) protein targeting to vacuole (IGI)
Cellular Component
High-throughput	integral to membrane (ISM)

interactions All VTH2 Interaction evidence and references

	12 total interaction(s) for 12 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-RNA: 1 PCA: 7
Genetic Interactions	Dosage Rescue: 1
Resources	BioGRID \| BOND \| BioPIXIE \| CYC2008 (complexes) \| Complexome \| DIP \| DRYGIN \| GeneMANIA \| InterologFinder

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Protein Information All VTH2 Protein evidence and references

Localization	YeastRC \| YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP \| YeastRC
Homologs	Ashbya (AGD) \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrX:11475 to 16124 | |

SGD ORF map

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..4650	11475..16124	1996-07-31	1996-07-31

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000003758

References cited on this page View Complete Literature Guide for VTH2

1)	Cooper AA and Stevens TH (1996) Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J Cell Biol 133(3):529-41
2)	Westphal V, et al. (1996) Multiple pathways for vacuolar sorting of yeast proteinase A. J Biol Chem 271(20):11865-70