VNX1/YNL321W Summary Help

Standard Name VNX1 1
Systematic Name YNL321W
Feature Type ORF, Verified
Description Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate (1, 2, 3)
Name Description Vacuolar Na+/H+ eXchanger 1
Chromosomal Location
ChrXIV:34696 to 37422 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All VNX1 GO evidence and references
  View Computational GO annotations for VNX1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
24 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 2
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Phenotypic Enhancement: 4
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 908
Molecular Weight (Da) 102,498
Isoelectric Point (pI) 7.13
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:34696 to 37422 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2727 34696..37422 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005265
References cited on this page View Complete Literature Guide for VNX1
1) Cagnac O, et al.  (2007) Identification and Characterization of Vnx1p, a Novel Type of Vacuolar Monovalent Cation/H+ Antiporter of Saccharomyces cerevisiae. J Biol Chem 282(33):24284-93
2) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
3) Manohar M, et al.  (2010) Zebrafish ( Danio rerio ) Endomembrane Antiporter Similar to a Yeast Cation/H(+) Transporter Is Required for Neural Crest Development. Biochemistry 49(31):6557-66