VAN1/YML115C Summary Help

Standard Name VAN1 1
Systematic Name YML115C
Alias VRG7 , VRG8 , LDB13
Feature Type ORF, Verified
Description Component of the mannan polymerase I; complex contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant (2, 3)
Name Description VANadate resistance protein 1
Chromosomal Location
ChrXIII:41794 to 40187 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 38 cM
Gene Ontology Annotations All VAN1 GO evidence and references
  View Computational GO annotations for VAN1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 9 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
61 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Co-fractionation: 2
  • Co-purification: 3
  • Reconstituted Complex: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Synthetic Growth Defect: 10
  • Synthetic Lethality: 23

Resources
Expression Summary
histogram
Resources
Length (a.a.) 535
Molecular Weight (Da) 61,091
Isoelectric Point (pI) 5.13
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:41794 to 40187 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 38 cM
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1608 41794..40187 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004583
References cited on this page View Complete Literature Guide for VAN1
1) Kanik-Ennulat C and Neff N  (1990) Vanadate-resistant mutants of Saccharomyces cerevisiae show alterations in protein phosphorylation and growth control. Mol Cell Biol 10(3):898-909
2) Jungmann J and Munro S  (1998) Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity. EMBO J 17(2):423-34
3) Stolz J and Munro S  (2002) The components of the Saccharomyces cerevisiae mannosyltransferase complex M-Pol I have distinct functions in mannan synthesis. J Biol Chem 277(47):44801-8