URB2/YJR041C Summary Help

Standard Name URB2 1
Systematic Name YJR041C
Alias NPA2 2
Feature Type ORF, Verified
Description Protein required for normal metabolism of the rRNA primary transcript; nucleolar protein; proposed to be involved in ribosome biogenesis (1, 2)
Name Description Unhealthy Ribosome Biogenesis 1
Chromosomal Location
ChrX:513763 to 510239 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All URB2 GO evidence and references
  View Computational GO annotations for URB2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
Resources
35 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 12

Genetic Interactions
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,174
Molecular Weight (Da) 135,116
Isoelectric Point (pI) 6.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:513763 to 510239 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3525 513763..510239 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003802
References cited on this page View Complete Literature Guide for URB2
1) Mnaimneh S, et al.  (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44
2) Dez C, et al.  (2004) Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol 24(14):6324-37