Standard Name	UNG1 1
Systematic Name	YML021C
Feature Type	ORF, Verified
Description	Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus (2, 3, 4, 5)
Name Description	Uracil DNA N-Glycosylase 1

Chromosomal Location	ChrXIII:230813 to 229734 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -16 cM

	View Computational GO annotations for UNG1
Molecular Function
Manually curated	uracil DNA N-glycosylase activity (IDA)
Biological Process
Manually curated	DNA repair (IMP)
Cellular Component
Manually curated	mitochondrion (IDA) nucleus (IDA)

Classical genetics
null	cell cycle progression through the G2/M phase transition: arrested gamma ray resistance: normal gamma ray resistance: decreased resistance to 4-aminofolic acid and sulfanilamide: decreased resistance to 5-fluorouracil: increased
reduction of function	mutation frequency: increased uracil-DNA glycosylase activity: absent resistance to sodium hydrogensulfite: decreased resistance to sodium nitrite: decreased
Large-scale survey
null	competitive fitness: decreased heat sensitivity: increased hyperosmotic stress resistance: decreased resistance to amitrole: decreased resistance to 5-fluorouracil: decreased resistance to cycloheximide: decreased toxin resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	42 total interaction(s) for 34 unique genes/features.
Physical Interactions	Two-hybrid: 1
Genetic Interactions	Dosage Growth Defect: 2 Negative Genetic: 13 Phenotypic Enhancement: 2 Phenotypic Suppression: 11 Positive Genetic: 4 Synthetic Growth Defect: 4 Synthetic Lethality: 1 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:230813 to 229734 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -16 cM
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1080 230813..229734 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004483